The government is set to headquarter its new Tech North Initiative in Manchester, with firms in the area hoping to gain worldwide attention.
Tech North will be located in Manchester's Northern Quarter, an area similar to Old Street, the part of London home to many technology start-ups.
On Thursday a government-backed report examined the growth of technology "clusters" around the UK.
The report suggested that as well as London, where the government has put considerable effort into promoting start-ups, other places such as Brighton, Liverpool, Belfast and Greater Manchester have shown strong growth in the digital industry.
The Tech Britain report has been published online as an interactive guide.
Prime Minister David Cameron said: "The digital economy has become an integral part of our country and the rapid growth of many digital businesses has confirmed Britain's position as a global hub of technology excellence."
George Osborne added: "What's so exciting about today's Tech Nation report is that it shows how we're seeing the growth of tech businesses right across the country.
"As part of our plan for a truly national recovery we will do everything we can to support this growth and back the different tech clusters that are emerging around Britain."
The arrival of Tech North Manchester comes five years after Mr Cameron announced Tech City, an organisation set up to support start-ups around the "Silicon Roundabout" in East London.
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